Siam Weed Leaf is found to be a highly efficacious medicinal herb according to the traditional medicinal systems. The same is proved by its pharmacological evaluation performed by scientific community across the world. In traditional medicine, the leaf is used as a many remedy, including astringent, antispasmodic, antihypertensive, powerful antioxidants, anti-inflammatory, antimicrobial activity, against staphylococci, diuretic, anti-diarrheal, antiulcer agent, reduces fever and heart tonic. The Siam Weed a traditional herbal treatment in some countries for burns, soft tissue wounds and skin infections, treatment of wounds. A formulation prepared from the aqueous extract of the leaves has been licensed for clinical use in Vietnam. Inhibition of collagen lattice by fibroblasts.